Lipsome lipid composition IC50 (µg)* R2# β-Glucan 13.94 0.959 PC 12.01 0.987 PC:Chol (6:1) 11.71 0.990 DDAB:DPPC:Chol (4:2:1) 12.34 0.983 DCP:DPPC:Chol (4:2:1) 13.26 0.976 DPPC:Chol (6:1) 11.07 0.988 DSPC:Chol (6:1) 9.516 0.940 DSPC 10.86 0.96

Note: * The concentration of β-Glucan necessary to produce 50% inhibition of cell growth. # R2=the square of the correlation coefficient. PC: L-α-Phosphatidylcholine; Chol: Cholesterol; DDAB: Didecyldimethylammonium bromide; DPPC: 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine; DCP: dicetyl phosphate; DSPC: 1, 2-Distearoyl-sn-glycero-3- phosphocholine. Table 2: Liposomal β-Glucan: The IC50 values were calculated using sigmoidal concentration-response curve-fitting methods (GraphPad Prizm 6 software) and the logit-log equation. In all cases, best fits were obtained with the coefficient of correlation R2 ranging from 0.94 to 0.99.