Items Normal range Serum levels Before treatment 1 month 2 months Liver function tests Bilirubin total 0.2-1.2 0.21 0.26 0.24 Bilirubin direct 0.0-0.3 0.03 0.11 0.11 SGPT Up to 50 37 27 22 Alkaline phosphatase <390 27 36 34 Albumin 3.8-5.4 3.5 4 3.3 SGOT Up to 37 32 27 29 Kidney function tests Blood urea 18-45 36 37 29 Serum creatinine <1.5 1.14 1.27 1.25 Serum uric acid 3.5-7.2 0.2 0.2 0.2

Table 1: Liver and kidney function before and after treatment of mammary gland tumor in a cat using photothermal therapy with gold nanorods.