%RM %NB %NBM %NBM+RM %CT %R %ARRM Sil-Oss® 9 ± 5% 32 ± 6% 80 ± 8% 89 ± 9% 11 ± 9% 86 ± 7 67 ± 8

%RM: percentage of remaining material %NB: percentage of new bone including mineralized bone and osteoid %NBM: percentage of new bone matrix including NB and bone marrow %NBM+RM: percentage of defect filled with new bone matrix and remaining material %CT: percentage of connective tissue. %R: percentage of material resorption %ARRM: percentage of average granule area reduction ±: confidence interval; n=9; α=0.05 Table 3: Results of the histomorphometric analysis after 16 weeks.