S.NO
Batch code
Initial Drug Content (%w/w) (mean ± SD*)
Drug content (%w/w)
After one month
After two months
After three months
At 25°C/60% RH (mean ± S.D*)
At45°C/70%RH (mean ± SD*)
At 25°C/60% RH (mean ± S.D*)
At45°C/70%RH (mean ± SD*)
At 25°C/60% RH (mean ± S.D*)
At45°C/70%RH (mean ± SD*)
1
PD1
90 ± 0.03
90 ± 0.01
89 ± 0.03
89.9 ± 0.05
88.6 ± 0.01
89.9 ± 0.02
87.9 ± 0.06
2
PD4
90.6 ± 0.05
90.6 ± 0.04
90.3 ± 0.04
90.6 ± 0.02
90.0 ± 0.04
90.5 ± 0.03
89.8 ± 0.02
3
PD13
97 ± 0.05
97 ± 0.02
96.8 ± 0.03
97 ± 0.04
96.7 ± 0.05
97 ± 0.03
96.5 ± 0.04
*n=3 SD: Standard deviation
Table 3:
Drug content of nanoparticles stored at different temperatures for 3 months.
