Group
N (Day 1/Day 8)
Day 1 mean ± SD
Day 8 mean ± SD
Difference (of means)
VII
6/6
9605.15 ± 3789.03
20816.27 ± 5006.76
11211.12
VIII
7*/4**
11589.22 ± 1756.67
13900.22 ± 4113.67
2510.99
IX
6/6
9320.15 ± 1665.68
7173.54 ± 1762.24
-2146.61
X
5*/4**
10643.59 ± 2085.07
8026.63 ± 1908.76
-3127.61
*1 subject transferred from Group X to Group VIII because treatment conforms to VIII
**2 subjects deceased in group VIII, another one in Group X
Table 3:
Tumor volume development (in mm) in the dosage-efficacy tests.
