Abbreviations: SD, standard deviation;

Figure 3: Cytotoxicity of IO/HSA-PEG-TRAIL NPs, IO-DVS-TRAIL NPs and free TRAIL (all with TRAIL concentration of 10 ng/ml) on A172 human GBM cells using LDH assay. Samples were incubated with non-heated serum to accelerate degradation (n=6, mean ± SD). **, p<0.01 from TRAIL.