Figure 1: Resveratrol triggers the differentiation of M1 to M2 macrophages.Gene expressionby M1 macrophages cultured under different resveratrolconcentration was analyzed by measuring the levels of (A) IL-6, (B) TNF-α,(C) IL-10, (D) VEGF, and (E) MRC-1using qRT-PCR. All experiments weredone in triplicate. Data points are plotted as mean ± SD (n=3). A single asteriskdenotes significantly (P ≤ 0.05) higher as compared to groups denoted bytwo asterisks. Two single asterisk denotes significantly (P ≤ 0.05) higher ascompared to groups denoted by three asterisks. Results demonstrated thehighest level M2 signatory genes in the presence of resveratrol demonstratingthe potential to drive the pro-angiogenic and anti-inflammatory response.