Material |
pH |
Zero Order |
First Order |
Higuchi |
|
|
R2 |
K0 (%, h-1) |
R2 |
K1(%, h-1) |
R2 |
KH (%, h-1) |
MCM-NH2-Cur |
2.5 |
0.9698 |
0.148 |
0.9743 |
0.002 |
0.9004 |
1.206 |
KCC-NH2-Cur |
2.5 |
0.9706 |
0.194 |
0.971 |
0.002 |
0.8707 |
1.58 |
MCM-NH2-Cur |
5 |
0.8776 |
0.078 |
0.8845 |
0.001 |
0.9415 |
0.651 |
KCC-NH2-Cur |
5 |
0.9775 |
0.162 |
0.9755 |
0.002 |
0.8515 |
1.312 |
MCM-NH2-Cur |
7.5 |
0.8847 |
0.057 |
0.8893 |
0.001 |
0.9337 |
0.475 |
KCC-NH2-Cur |
7.5 |
0.9645 |
0.129 |
0.9588 |
0.001 |
0.7914 |
1.029 |
|
R2: correlation coefficient, K0: zero-order rate constant, K1: first-order rate constant, KH: Higuchi rate constant |
Table 2: Kinetic parameters of curcumin release from silica materials as drug carrier systems under different pH conditions based on several mathematical models. |