Material |
pH |
Korsmeyer-Peppas model |
Mechanism |
K(h-n) |
R2 |
n |
MCM-NH2-Cur |
2.5 |
0.292 |
0.9810 |
0.841 |
non-Fickian or anomalous diffusion |
KCC-NH2-Cur |
2.5 |
0.272 |
0.9729 |
0.921 |
zero-order mechanism |
MCM-NH2-Cur |
5 |
0.375 |
0.9607 |
0.634 |
non-Fickian or anomalous diffusion |
KCC-NH2-Cur |
5 |
0.164 |
0.9775 |
0.998 |
zero-order mechanism |
MCM-NH2-Cur |
7.5 |
0.255 |
0.9565 |
0.651 |
non-Fickian or anomalous diffusion |
KCC-NH2-Cur |
7.5 |
0.053 |
0.9751 |
1.205 |
zero-order mechanism |
|
K: rate constant, R: correlation coefficient, n: release exponent |
Table 3: The Korsmeyer–Peppas model fits of curcumin release from two types of MSNs under different pH conditions. |