| Drug |
Microorganism |
Mechanism of resistance |
| β-lactum (carbapen) |
Enterobactericeae(E.coli) |
Drug degrading enzyme |
| β-lactum (methicillin) |
Staphylococcus aureus |
Production of an additional enzyme that avoids binding |
| Macrolide |
Streptococcus pneumoniae |
Drug efflux pump |
| Vancomycin |
Enterococcus |
Changes in target |
| Multiple drugs |
Pseudomonas aeruginosa |
Loss of porin |
| Vancomycin |
Staphylococcus aureus |
Cell wall thickening changes in target |
| Quinolone |
Gonococci |
Mutation in target |
| Sulfonamide |
Enterococcus |
Over production of target site |
|
