Doxil®
PEGADRIA
Unilamellar
99.7%
99.0%
AED (Mean)
51.4 nm ± 12.0 nm
55.8 nm ± 13.66
Circularity (Mean)
0.84 ± 0.06
0.87 ± 0.07
Loaded
98.4%
98.8%
Bilayer thickness
~7 nm
~7 nm
PEG Layer Thickness
~3-5 nm
~3-5 nm
AED: area diameter
Table 2:
Morphology of PEGADRIA and Doxil® by Electron Microscopy Studies.