Figure 4: Enhancement of EBD tumor permeability in response to SMAZnPP photosensitization. (A) EBD concentration in S-180 murine sarcoma without PDT (B) After injection of 5mg/kg ZnPP photosensitizer, followed by 5 minutes light irradaition at 50.000 Lux. The arrows point to areas of vascular inflammation, scale bar: 5 cm. (C) Representative tubes of the extracted EBD from light irradiated and non-irradiated animals. (D) The difference between extracted EBD with light irradiation was almost 3 folds higher compared to no irradiation.