| |
TotalCells (× 105) |
Macrophages |
Neutrophils |
Eosinophils (% of Total cell count) |
Lympocytes (% of Total cell count) |
Epitheila Cells (% of Total cell count) |
| (% of Total cell count) |
(% of Total cell count) |
| Naive |
3.2 ± 0.6 |
99.1 ± 0.2 |
0.1 ± 0.1 |
0.0 ± 0.0 |
0.0 ± 0.0 |
0.8 ± 0.2 |
| Citrate Vehicle |
2.7 ± 0.5 |
95.9± 0.7 |
0.1 ± 0.1 |
0.1 ± 0.1 |
0.2 ± 0.1 |
3.8 ± 0.7a |
| AgNP (1day) |
4.1 ± 0.6 |
90.8 ± 7.7 |
7.8 ± 7.7 |
0.0 ± 0.0 |
0.7 ± 0.7 |
0.7 ± 0.4b |
| AgNP (7day) |
3.7 ± 0.7 |
89.1 ± 5.1 |
8.9 ± 5.1 |
0.4 ± 0.2 |
0.8 ± 0.3 |
0.8 ± 0.4b |
| AgAc |
6.1 ± 1.1a,b,c,d |
57.6 ± 10.8 |
37.8 ± 10.2a,b,c |
0.2 ± 0.2 |
3.9 ± 1.1 |
0.5 ± 0.4 |
| (1day) |
|
Note: Total cells and reletive percentage of macrophages, neutrophils, eosinophils, lyphocytes, and epithelial cells present in BAL fluid following IT instillation of citrate
vehicle or 200 μg in 200 μl installation blous of 20 nm silver naoparticle (AgNP) or silver acetate (AgAc). Statistical significance p<0.05 compared to anaïve, bCitrate vehicle,
c1 day AgNP, determined by one way ANOVA with Tukey post hoc test. Data displayed as mean ± SEM, n=4–5.>
Table 1: Bronchoalveolar lavage cell differentials: Total cell number and relative percentage of macrophages, neutrophils, eosinophils, lyphocytes, and epithelial cells
present in BAL fluid following 200 μl IT instillation of citrate vehicle, 200 μg 20 nm AgNP or silver acetate (AgAc). Statistical significance was determined as p<0.05
compared to naïve a or citrate vehicle b by one way ANOVA with Tukey post hoc test. n=4–5. Data reported as mean ± SEM. |
