| Variables |
Level of variables |
| Independent variables |
Low (-1) |
Medium (0) |
High (+1) |
| A = Drug to lipid ratio |
1:2 |
1:3 |
1:4 |
| B = Surfactant (%) |
1 |
1.5 |
2 |
| C = Stirring speed (RPM) |
2000 |
2500 |
3000 |
| Dependent variables |
Goals |
| Y1 = Particles size |
Minimize |
| Y2 = % D E |
Maximize |
| Y3 = % D L |
Maximize |
|
