| Formulation code
|
Coded value |
Actual value |
| A |
B |
C |
Drug to lipid ratio |
SurfactantConc. (%) |
Stirring speed (rpm) |
| H1 |
-1 |
-1 |
0 |
1:2 |
1 |
2500 |
| H2 |
1 |
-1 |
0 |
1:4 |
1 |
2500 |
| H3 |
-1 |
1 |
0 |
1:2 |
2 |
2500 |
| H4 |
1 |
1 |
0 |
1:4 |
2 |
2500 |
| H5 |
-1 |
0 |
-1 |
1:2 |
1.5 |
2000 |
| H6 |
1 |
0 |
-1 |
1:4 |
1.5 |
2000 |
| H7 |
-1 |
0 |
1 |
1:2 |
1.5 |
3000 |
| H8 |
1 |
0 |
1 |
1:4 |
1.5 |
3000 |
| H9 |
0 |
-1 |
-1 |
1:3 |
1 |
2000 |
| H10 |
0 |
1 |
-1 |
1:3 |
2 |
2000 |
| H11 |
0 |
-1 |
1 |
1:3 |
1 |
3000 |
| H12 |
0 |
1 |
1 |
1:3 |
2 |
3000 |
| H13 |
0 |
0 |
0 |
1:3 |
1.5 |
2500 |
| H14 |
0 |
0 |
0 |
1:3 |
1.5 |
2500 |
| H15 |
0 |
0 |
0 |
1:3 |
1.5 |
2500 |
| H16 |
0 |
0 |
0 |
1:3 |
1.5 |
2500 |
| H17 |
0 |
0 |
0 |
1:3 |
1.5 |
2500 |
|
