| Result of the analysis of variance |
Particle size (nm) (Y1) |
Entrapment efficiency (%) (Y2) |
Drug loading (%) (Y3) |
| Regression |
| Some of square |
22286.24 |
251.37 |
204.42 |
| Degrees of freedom (df) |
9 |
9 |
9 |
| Mean squares |
2476.25 |
27.93 |
22.71 |
| F-value |
7288.58 |
69.33 |
323.46 |
| P |
<0.0001 |
<0.0001 |
˂0.0001 |
| Inference |
Significant |
Significant |
Significant |
| Lack of fit tests |
| Some of square |
0.37 |
0.20 |
0.36 |
| Degrees of freedom (df) |
3 |
3 |
3 |
| Mean squares |
0.12 |
0.065 |
0.12 |
| F-value |
0.24 |
0.099 |
3.64 |
| P |
0.8618 |
0.9563 |
0.1221 |
| Inference |
Non- Significant |
Non- Significant |
Non-Significant |
| R2 |
0.9999 |
0.9889 |
0.9976 |
| Correlation of variation (% CV) |
0.27 |
0.95 |
1.41 |
| Residual |
| Some of square |
2.38 |
2.82 |
0.49 |
| Degrees of freedom (df) |
7 |
7 |
7 |
| Mean squares |
0.34 |
0.40 |
0.070 |
| Standard deviation (SD) |
0.58 |
0.63 |
0.26 |
|
