Modified log-logistic model1 Yeast strain ED50 b2 c3 d4 e5 f6 Untransformed yeast 0.04 5.76 0.15 1.17 0.08 2.07   (0.004)7 (-1.8) (-0.06) (-0.06) (-0.004) (-0.96) Transformed Plasmid 0.07 3.21 –0.01 0.64 0.02 20.66*   (-0.007) (-0.6) (-0.04) (-0.07) (-0.002) (4.06) Transformed Sensitive (418) 0.05 2.51 –0.30 1.31 0.17 1.78   (-0.007) (-0.8) (-0.36) (-0.06) (-0.029) (-1.08) Transformed Resistant (940) 0.02 1.65 –0.00 0.89 0.01 25.87*   (-0.043) (-0.2) (-0.06) (-0.07) (0.006) (-17) Transformed Resistant (292) 0.09 2.89 0.28 1.12 0.04 6.93*   (-0.005) (-0.6) (-0.06) (-0.07) (-0.005) (-2.15)

Table 4: Dose-response parameters and ED50 (medium effective dose reducing growth by 50%) for non-transformed and transformed yeast R-1 strain in yeast extract-peptone-dextrose (YPD) broth amended with tetraconazole The parameters were determined using a Cedergreen-Ritz-Streibig modified loglogistic model [45].