IgA Secretory IgA produced by mucosal tissues and fallopian tubes [67] Inhibits microbial adherence to surfaces
Agglutinating resident microbes [68,69]
    Reducing the hydrophobic nature of the microbes [70]
    Blocking microbial adhesions [71]
    Rendering viruses ineffective. Aggregating virus particles [72]
    Neutralizing microbial toxins and enzymes.  Blocking binding to target cells [73]   
    Inhibiting penetration of antigen into the mucosa.  Binding soluble antigens and facilitating removal by mucus flow [68]
    Opsonization of microbes for mucosal phagocytes.  Coating pathogen with IgA [68]
    Stimulating antibody-assisted cell-mediated immunity.  Inducing complement-independent antibacterial action of monocytes [74]
    Augmenting T-cell antimicrobial activity (specifically against T cells) [75]
    Promoting activity of innate immunity [76]
    Increasing microbe trapping of mucin by mimicking microbe receptor sites [77]
IgG Transudate from blood stream [67]
Actively transported [78]
Locally produced [79]
Direct action against bacteria and viruses.  Immune exclusion of HIV particles [80]; binding, agglutination of bacteria,  complement activation [81]   
Ig = immunoglobulin
Table 1: Components of Humoral Immunity in the Lower Female Reproductive Tract.