| Hormone or binding protein |
Younger adults |
Older adults |
Men |
Reference |
Women
(Premenopause) |
Reference |
Men |
Reference |
Women
(Postmenopause) |
Reference |
| DHEAS |
≈ 12 µmol/L
Age 20 yrs |
[159] |
≈ 6 µmol/L
Age 20 yrs |
[159] |
≈ 3 µmol/L
Age 60 yrs |
[159] |
≈ 1.5 µmol/L
Age 60 yrs |
[159] |
| |
8.5 µmol/L
(3110 ng/mL )
Age < 40 yrs |
[160] |
7.7 µmol/L
(2824 ng/mL)
Age < 40 yrs |
[160] |
1.5 µmol/L
(551 ng/mL)
Age 90-99 |
[160] |
1.0 µmol/L
(364 ng/mL)
Age 90-99 |
[160]
Age 90-99 |
| |
7.0 ± 4.0 µmol/L
(2600 ± 1500 ng/mL)
Ages 40-70 |
[13] |
3.64 µmol/L
(95% CI 1.6–1.72) |
[161] |
4.3 ± 2.7 µmol/L
(1600 ± 1000 ng/mL)
Ages 46-80 |
[13] |
1.9 nmol/L
(95% CI 0.8 – 4.4)
Median age, 54 |
[14] |
| DHEA |
20 – 25 nmol/L
Age 20 - 30 |
[162] |
20-27 nmol/L
Age 20 - 30 |
[162] |
4 – 6 nmol/L
Ages 50 - 80 |
[9] |
6 – 7 nmol/L |
[9] |
| Total testosterone |
13 – 40 nmol/L
Age 30 |
[163] |
0.6 – 2.5 nmol/L
(0.2 - 0.7 ng/mL)
Age unspecified |
[162] |
6 – 26 nmol/L
Age 80 |
[163] |
0.56 ± 0.26 nmol/L
Ages 50-89 |
[22] |
| |
18.0 ± 6.1 nmol/L
(5.2 ± 1.8 ng/mL)
Ages 40-70 |
[13] |
1.66 nmol/L
(95% CI 1.6–1.72)
Ages < 50 |
[161] |
15.7 ± 5.6 nmol/L
(4.5 ± 1.6 ng/mL)
Ages 46-80 |
[13] |
1.4 nmol/L
(95% CI 0.6 – 2.4)
Median age, 54 |
[14] |
| |
22 ± 7 nmol/L |
[164] |
1.2 ± 0.7 nmol/L |
[165] |
15.8 ± 0.17 nmol/L
(4.57 ± 0.05 ng/mL)
Ages 69-80 |
[10] |
0.5 ± 0.01 nmol/L
(0.14 ± 0.004 ng/mL)
Ages 55-65 |
[10] |
| Free testosterone |
0.097 ± 0.039 ng/mL
(0.34 ± 0.14 nmol/L)
Ages 40-70 |
[13] |
12.8 ± 5.5 pmol/L |
[165] |
0.075 ± 0.032 ng/mL
(0.26 ± 0.11 nmol/L)
Ages 46-80 |
[13] |
0.14 ± 0.07 nmol/L
Ages 50-89 |
[22] |
| DHT |
0.91 ± 0.58 nmol/L
(0.26 ± 0.17 ng/mL)
Ages 40-70 |
[13] |
0.43 nmol/L
(0.12 ng/mL)
Ages 30-49 |
[166] |
1.19 ± 0.70 nmol/L
(0.35 ± 0.20 ng/mL)
Ages 46-80 |
[13] |
0.22 ± 0.11 nmol/L
(62.4 ± 32 pg/mL)
Age ≤ 69 |
[167] |
| SHBG |
32 ± 16 nmol/L
Ages 40-70 |
[13] |
53.1 nmol/L
(95% CI 50.7–50.5)
Ages < 50 |
[161] |
32 ± 16 nmol/L
Ages 46-80 |
[13] |
50.5 nmol/L
(95% CI 21.0–99.8)
Median age, 54 |
[14] |
| Estradiol |
84.0 ± 22.4 pmol/L
Ages 24-31 |
[39] |
381 pmol/L
(95% CI
356 –407.6) |
[161] |
88.1 ± 24.6 pmol/L
Ages 70-79 |
[39] |
18 ± 9 pmol/L
Ages 50-89 |
[22] |
| |
81.5 ± 23.1 pmol/L
Ages 37-46 |
[39] |
|
|
79.0 ± 1.1 pmol/L
(21.5 ± 0.3 pg/mL)
Ages 69-80 |
[10] |
15.4 ± 0.7 pmol/L
(4.2 ± 0.2 pg/mL)
Ages 55-65 |
[10] |
| Estrone |
156 ± 75 pmol/L
Age 40-70 |
[13] |
409.9 pmol/L
(95% CI
383.4 –436.4) |
[161] |
124 ± 78 pmol/L
Age 46-80 |
[13] |
70 ± 34 pmol/L
Ages 50-89 |
[22] |
| |
|
|
|
|
139 ± 2 pmol/L
Ages 69-80 |
[10] |
65.9 ± 1.8 pmol/L
Ages 55-65 |
[10] |
