Prohormone or hormone
Change with advancing age
Men
Women
DHEAS
Substantial decrease
Substantial decrease
DHEA
Decrease
Decrease
Testosterone
Decrease
Decrease
DHT
No significant change
No significant change
Estradiol
No significant change
Substantial decrease
Estrone
No significant change
Decrease
Table 2:
Trends in circulating levels of sex steroids in aging men and women.