Skin structure
Enzyme acitvity
Sex steroid receptors
17 β-HSD
3β-HSD
5α-reductase
Aromatase
AR
ERβ
ERα
Epidermal keratinocytes
+ (4- isotypes)
+ (1- isotype)
+
Melanocytes
Hair follicles
+ (1- isotype) (2- isotype in beard)
Follicular keratinocytes
Root sheath
+ (2- isotype)
Matrix epithelium
Dermal papilla cells
Sebaceous glands
+ (3- and 5- isotypes)
Sweat glands
Eccrine
Apocrine
Dermal fibroblasts
Endothelial cells