Cofactor |
Full Name |
Interaction with ER |
References |
AIB3 |
Amplified in breast cancer 3 |
Binds ER AF-2 through LXXLL motifs |
[10] |
ARNT |
Aryl hydrocarbon receptor nuclear translocator |
Binds ERa LBD |
[11] |
BRG-1 |
Brahma-related gene 1 |
Binds ERa AF-2 domain |
[12] |
BCAS2 |
Breast cancer amplified sequence 2 |
ND |
[13] |
CIP1 |
Clin-dependent kinase inhibitor 1A |
ND |
[14] |
Ciz1 |
Cip-interacting zinc finger protein 1 |
Binds ERa DBD |
[15] |
E6-AP |
E6-associated protein |
Binds ERa AF-2 |
[16] |
ERIAP |
Estrogen Receptor Interacting and Activating Protein |
Binds ERa LBD/AF-2 |
[17]. |
HER4 |
Proto-oncogene-like protein c-ErbB-4 |
Binds ERa AF-1 or AF-2 |
[18] |
hMMS19 |
|
ND |
[19] |
ING1b |
Inhibitor of growth family, member 1 |
ND |
[20] |
IRS-1 |
Insulin receptor substrate 1 |
Binds ERa AF-1 or DBD |
[21] |
LRP16 |
Leukemia related protein 16 |
Binds ERa AF-1 |
[22] |
Menin |
Multiple endocrine neoplasia type 1 |
Binds ERa AF-2 |
[23] |
MICoA |
MTA1-interacting coactivator |
Binds ERa AF-2 through LXXLL motifs |
[24] |
MUC1 |
mucin 1, cell surface associated |
Binds ERa DBD |
[25] |
Pak1 |
p21-activated kinase 1 |
Binds ERa AF-1 or AF-2 |
[26] |
PELP1 |
proline-,glutamic acid-,and leucine-rich protein-1 |
Binds ERa AF-2 through LXXLL motifs |
[27] |
p68 |
p68 RNA helicase |
Binds ERa AF-1 |
[28] |
p300 |
Histone acetyltransferase p300 |
Binds ERa AF-2 through LXXLL motifs |
[29] |
SIRT1 |
sirtuin 1 |
ND |
[30] |
SRC1 |
Steroid receptor coactivator 1 |
Binds ERa AF-2 through LXXLL motifs |
[31] |
SRC-3 |
Steroid receptor coactivator-3 |
Binds ERa AF-2 through LXXLL motifs |
[32] |
SRA |
Steroid receptor RNA activator |
Binds ERa AF-1 |
[33] |
TIF1 |
Transcriptional intermediary factor 1 |
Binds ERa AF2 domain |
[34] |
TIF2 |
Transcriptional intermediary factor 2 |
Binds ERa AF-2 through LXXLL motifs |
[35] |
TRAP220 |
Thyroid hormone receptor activating protein of 220 kDa |
Binds ER AF-2 through LXXLL motifs |
[36] |
XBP-1 |
X-box binding Protein l |
Binds ERa DBD |
[37] |