Concentration (pg/ml) Visit 1 Visit 2 P- value IL-6 113.9 (139.4) 79.7 (85.9) 0.27 IL-8 755.3 (906.1) 611.8 (757.2) 0.72 HB-EGF 609.6 (298.1) 679.8 (457.2) 0.54

Table 1: Concentrations of inflammatory mediators (IL-6, IL-8 and HB-EGF) in induced sputum.