**Table 4: **Modulation of End Point Biomarkers in Model for Triple Negative Breast Cancer. ^{a}I3C at its maximum cytostatic concentration. ^{b}Concentration of individual E2 metabolites determined by the tritium exchange assay after a 48 hr treatment. Mean±SD, N=3 per treatment group. Data analyzed by the 2-sample t test comparing the data from the DMSO group (Control). ^{c}Anchorage independent (AI) colony counts at day 21 post-seeding of 1,000 cell per well of six well plates. MeanĀ±SD, N=18 per treatment group. Data analyzed by the 2-sample t test comparing the data from the DMSO group (Control). ^{d-e}P= 0.001. ^{f-g}P=0.01. |