promotes
Figure 3: PPARδ promotes growth of human breast cancer cells. (A) MCF-7, ZR-75 and T47D cells or (B) HeLa cells were seeded in 96-well plates and treated with vehicle (Veh) (ethanol), 17β- estradiol (E2) (10 nM), carbaprostacyclin (Carb) (1 μM), GSK660 (1 μM) or a combination of agents for 96 h. Cells were harvested for proliferation assays. Graphical data are represented as % increase in cell number over vehicle (set at 100%). Data points represent the average of quadruplicate samples for each condition in a representative experiment. (C) MDA MB-231 cells were seeded in 96-well plates and treated as indicated for 48 h. Cell proliferation (quadruplicate samples per treatment) was assayed and analyzed as above.