Figure 2: Unilateral microinfusion (0.3 μl) on dorsal hippocampus of vehicle (Veh., cylcodextrin 30% in aCSF) or steroid (A, P, Epoxy 1 and Epoxy 2 ; 2 μg) and changes in open-field behavioral parameters: a Active time (difference between total time test and freezing in sec) b Line crossing (number of grid lines crossed with all four paws), c Grooming (when the animal licks or scratches itself while stays still in sec) and d ratio (duration/frequency) and e Rearing (when the animal stands up on its hind legs in sec), and f ratio (duration/frequency). Significant effect was determined by one-way ANOVA: FActive time(4,35)=15.3; p<0.001, FLine crossing(4,35)=18.2; p<0.001, FGrooming(4,35)=2.8; p<0.05, FGrooming ratio(4,24)=1.1; p=0.12, FRearing(4,35)=13.3; p<0.001 and FRearing ratio(4,28)=0.5; p=0.75, sub index in each F indicates the variable analysed. * p<0.05 Newman-Keuls post hoc test.