Figure 3: Divergence of the 5-flanking sequences of AR/Ar. A. Dot plot of the mouse Ar and human AR relative to the rat Ar locus. In this plot, sequences with high similarity were plotted in a 50-bp window. B. Sequence comparison of 5 region (-15 kb to +2 kb) and CDS of AR/Ar across species using the BLASTZ algorithm. Data were visualized with the software GenomeJACK ( Each colored bar in the row for the indicated species represents a particular chromosome where the sequence best matched to the human genomic sequence in the red bar is located. Asterisks denote half-sites of consensus estrogen responsive element (5-GGTCAnnnTGACC-3: [114]).