Anion TcruCA hCA II SspCA
Ki(mM)a
Hg2+ 8.40 0.85 0.77
HSO3- 0.97 89 21.1
SO32- 7.6 7.5 2.3
HS- 0.70 0.04 0.58
TcruCA: α-CA isolated from Thiomicrospira crunogena XL2 [15]; hCA II: α-CA from humans (isoform II); SspCA: α-CA isolated from Sulfurihydrogenibium yellowstonense YO3AOP1 [18]; aInhibition contstants adapted from Mahon et al. [14]
Table 1: Selected anion inhibition constants of CAs suggested as CDR-agents.