MMP
-3
MMP-10
MMP-13
TCPS
1.77* 10
-4
2.53* 10
-4
2.17* 10
-4
TCPS + TGFß
1.2*10
-3
6.35*10
-3
1.04* 10
-2
induction
6.7-fold
25.1-fold
48.2fold, p<0.011
Col-1
1.32* 10
-4
2.75* 10
-4
2.13* 10
-4
Col-1 + TGFß
7.41**10
-4
9.89* 10
-3
1.77* 10
-2
induction
5.6-fold
36.0-fold
83.2-fold, p<0.03
LM-111
1.78* 10
-4
2.68* 10
-4
2.2* 10
-4
LM-111 + TGFß
1.1* 10
-3
5.84* 10
-3
1.77* 10
-2
induction
5.7-fold, p<0.028
20.4-fold, p<0.026
80.5-fold, p<0.04
Table 1:
Mean of normalized steady state transcript levels of MMP
-3
, MMP-10, and MMP13 in MSC (cells from nine donors each) grown in tissue culture polystyrene dishes (TCPS), or in dishes coated with type l collagen (Col-1) or laminin-111 (LM- 111).