Damage frequency (DF) Damage index (DI)   Patients Non-induced Induced Non-induced Induced 1 13.0 ± 5.44 23.8 ± 6.61 17.5 ± 3.88 33.0 ± 3.74 2 25.0 ± 10.80 51.5 ± 9.74 26.8 ± 12.20 72.8 ± 26.40 3 22.3 ± 9.07 67.0 ± 14.40 24.0 ± 11.10 165.6 ± 66.90 Means 20.11 ± 8.44 47.43 ± 10.26* 22.77 ± 9.06 90.49 ±32.34* *Significant difference as compared to non-induced control group at P < 0.01/t-student test

Table 2: Evaluation of DNA damage by the comet assay. Non-induced - ADAS cells grown under control conditions in DMEM, 10% FBS, 1% streptomycinpenicillin and 0.1% gentamycin. Induced - ADAS cells after 24 h culture in neuronal induction medium.