**Figure 4:** Effects of EFs on elastic matrix synthesis by VSMCs after 21 days
of culture. (A) Tropoelastin measured from spent media aliquots. (B) Matrix
elastin quantified from cell layers represented in terms of alkali–soluble
elastin, alkali–insoluble elastin, and total matrix elastin (soluble+insoluble).
Addition of EFs resulted in a 2.6 ± 1.4 (p=0.004) fold increase in total matrix
elastin, primarily in the form of soluble matrix elastin (p=0.04). ‘*’ represents
significant difference from comparable control for (p<0.05). |