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Figure 3: Detailed sketch of moving cell-sheet–bearing tray and roller device. The incubated cell-sheet–bearing plastic tray is first coated with PNIPAMgelatin, followed by cell seeding and culture. Both upper sides of tray have racks that can be engaged with pinions attached to the gelatin-coated roller. The tray is sliding on the roller bearing installed at the base matrix of the fabrication unit. Cold water is infused in a pipe embedded in base matrix, which allows local reduction of temperature. Multiple rotation of roller produces tubular ascular tissue mimics. |