Figure 9:HuESC were treated to brief exposure to 670C for 10 minutes to induce heat shock. The cellular response to heat shock includes the transcriptional up-regulation of genes encoding heat shock proteins (HSPs) as part of the cell's internal repair mechanism [30]. They are also called stress-proteins [31] and respond to heat, cold and oxygen deprivation by activating several cascade pathways. [32-35] Mixed phenotype in SAGM with transient hear shock (BJnhem20)