tibia radius femur clavaria (diameter) mandibular
rabbit 8 [59] 15 [60] 15 [61] 20 [62] 15 × 10 [63]
rat 5 [64] 5 [65] 6 [66] 8 [47] 5 (diameter) [67]
mouse NA NA 5 [68] 4 [69] 4 (diameter) [70]
sheep 50 [71] NA 25 [72] 22 [73] 35 (diameter) [74]
dog NA 25 [75] 21 [76] 20 [47] 47 18x10 [77]
pig 20 [23] NA NA 9  [78] 50  [79]
Table 1: Summary of critical size defect (mm) in different anatomic site of animals; NA=not available.