In animal Nos. 1, 3, and 4, the surfaces of the implanted defects were covered with the abundant cartilaginous white tissue (f, h, i), whereas the surfaces of the implanted defects were depressed, and the cartilaginous tissues was scarce in animal Nos. 2 and 5(g, j). Furthermore, synovium adhered to the defect in animal No.2 (g). On the other hand, the defects of the control sites were largely depressed in all animals (a, b, c, d, e). Gross pathology in the implanted sites of animal Nos. 1, 3, and 4 showed higher scores at the points of cartilage, including the coverage, the smooth surface, disappearing margin, and the color. However, there were no significant differences in the outcome measures of ICRS gross scores (B).
