Group Scaffold Osteoinductive agent Anti-resorptive agent Mice Exclusions
1 Porous PLGA rhBMP-2 (10µg) None N=8 2
2 Porous PLGA rhBMP-2 (10µg) PS-1145 (low 40µg) N=8 1
3 Porous PLGA rhBMP-2 (10µg) PS-1145 (high 80µg) N=8 3
4 Porous PLGA rhBMP-2 (10µg) PS-1145 (systemic 50mg/kg) N=8 1
Table 1: Study Details.