Static Measurements
BV/TV M Bone volume per total volume
Tb.Th M Trabecular thickness
Tb.N C Trabecular number
Tb.Sp C Trabecular separation
Dynamic Measurements
L2_only/BS M Second injected label per bone surface
L1_only/BS M First injected label per bone surface
sLS/BS M Single label surface per bone surface
dLS/BS M Double label surface per bone surface
LS/BS C Labeled surface (single or double) per bone surface
MS/BS C Mineralizing surface per bone surface
sLD/LS C Proportion of labeling surface that are single label
dLS/LS C Proportion of labeling surface that are double label
dLS/sLS C Ratio of double to single labeled surface
Ir.L.Th M Interlabel thickness
MAR C Mineral apposition rate (mm/day)
BFR C Bone formation rate (MAR x (MS/BS))
Cellular Measurements
AP/BS M Fraction of bone surface with AP label
AP_R/BS M Fraction of bone surface with AP activity and the second mineralization label
AP_only/BS M Fraction of bone surface with AP activity but without the second mineralization label
TRAP/BS M Proportion of the bone surface with proximal TRAP activity (25.6 mm distance)
TRAP_R/BS M Proportion of the bone surface with proximal TRAP activity and the second mineralization label
TRAP_only/BS M Proportion of the bone surface with proximal TRAP activity but without the second mineralization label
TRAP/TV M Total TRAP activity within the selected ROI
TRAP_on/TRAP C Proportion of total TRAP activity that is adjacent to the bone surface
M=measured value, C=calculate value from other measurements
Table 2: Definition of Histomorphometric Measurements.