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Figure 3: An example of MRI assessment of human chondrocytes seeded in alginate beads (a) T1 (b) T2 and (c) ADC values over the period of four weeks. T1 decreased by 6%, T2 increased by 8% and ADC values decreased by 5%. In a separate experiment, it was confirmed that stiffness increased from 2.8 kPa to 3.8 kPa from week 2 to week 4 confirming the production of proteoglycans and collagen. |