Figure 3: Epidermal and dermal immunohistochemical analyses of skin substitutes. Immunolabelling of epidermal differentiation markers (A) and extracellular matrix (B) of substitutes produced with the self-assembly approach. NHS: normal human skin; RSS: reconstructed skin substitute (scale bar = 50 μm). The dotted line indicates the dermo-epidermal junction. Reproduced and modified from Jean et al., 2011 according to the copyright policy of the publisher.© 2011 Mary Ann Liebert, Inc.