Vaccine
(rabbit numbers)

Papilloma sites

Protection sites

Protection rate

CRPVE1/161-169
(N=4)

16

0

0/16
(0%)

CRPVE1/303-311
(N=4)

5

11

11/16
(69%) a

CRPVE1/245-253
(N=4)

16

0

0/16
(0%)

CRPVE1/42-50
(N=4)

12

4

4/16
(25%) b

CRPVE1/149-157
(N=4)

8

8

8/16
(50%) a

HPV16E7/82-90
(N=4)

16

0

0/16
(0%)

aP=0.01 and bP=0.02 vs. HPV16E7/82-90 group, Fisher’s exact test
Table 2: Protective immunity induced by half-dose (12 shots) epitope DNA vaccination in outbred HLA-A2.1 transgenic rabbits.