Figure 8: Immunization with TcSP2 protects heart from infiltration of inflammatory cells after parasite challenge. Hearts from immunized and unimmunized mice were aseptically removed 42 days after parasite challenge, and fixed and embedded in paraffin. Tissue sections were subjected to staining with hematoxylin and eosin and visualized by light microscopy (10x). Representative microphotographs of heart tissue section from normal mice (A), mice immunized with rTcSP2 (B), and unimmunized and infected mice (C, D) are shown. Foci of inflammatory cells are identified with an arrow (D).