Figure 8: Characterization of antibody isotypes and specificity after J or G (derG)-LEAPS vaccine immunization and antigen challenge. Panel A. Antibodies generated in CEL-2000 immunized or unimmunized mice in the CIA model, adapted from [9]. Panel B. Antibodies generated after HSV infection of animals immunized with JgD, adapted from [6]. Panel C. Antibodies generated following immunization with J-MY1, adapted from [10]. Panel D. Antibodies produced by HSV infected mice following immunization with HSV JgB, GgB or gB, adapted from [7].