Figure 8: Characterization of antibody isotypes and specificity after J or G (derG)-LEAPS vaccine immunization and antigen challenge.
Panel A. Antibodies generated in CEL-2000 immunized or unimmunized mice in the CIA model, adapted from [9].
Panel B. Antibodies generated after HSV infection of animals immunized with JgD, adapted from [6].
Panel C. Antibodies generated following immunization with J-MY1, adapted from [10].
Panel D. Antibodies produced by HSV infected mice following immunization with HSV JgB, GgB or gB, adapted from [7].