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Figure 2: PBMC proliferation analysis. Cell proliferation index of 3 patient groups (HER2 0, HER2 1+2+, and HER2 3+) and a healthy donor group (HD) are shown. HD, healthy donors (n=22); HER2 0, patients with HER2 expression immunohistochemistry (IHC) score 0 (n=66); HER2 1+2+, patients with HER2 expression IHC scores 1+ and 2+ (n=89); and HER2 3+, patients with HER2 expression IHC score 3+ (n=18). Open circles represent each patient’s cell proliferation index. The solid bar represents the mean value of each group. Significant difference between HD and each patient group is shown with * (p<0.05) and ** (p<0.001). |