Vaccination Group Percent survival of immunised or sham-immunised mice post- intranasal challenge [CFU/20 mL/mouse] with virulent B. pertussis
4.2×107 4.2×108 4.2×109 4.2×1010
aroQBP [i/n*- 1 dose] 100 100 100 100
DTaP [s/c**-1 dose] 100 100 100 67
PBS [s/c-1 dose] 67 33 0 0
PBS [i/n*-3 doses] 50 33 17 0
i/n denotes intranasal; s/c* denotes subcutaneous.
Table 3: Protective efficacy of a single dose of aroQ B. pertussis against intranasal challenge of immunised mice with virulent B pertussis at day 28 post-immunisation.