Group Tx-vac-flu (n=8) Tx-no vac-flu (n=6) Healthy-flu (n=12) Tx-vac-no flu (n=13) Pneumonia (n [%]) 6 [33%] 0 [0%] 0 [0%]* N/A Hospitalization (n [%]) 15 [83%] 5 [83%] 1 [8%]† Length of hospitalization in days Median Mean Range 7.2 4 2-30 3.4# 3 3-4 N/A Admission to an ICU (n [%]) 1 [6%] 0 [0%] 0 [0%] Need for mechanical ventilation (n [%]) 1 [6%] 0 [0%] 0 [0%] **FEV1 (L) change (median ) at a later date + 0.035 - 0.73 N/A - 0.22 Tx-vac-flu=Transplant recipients who developed influenza despite influenza vaccination Tx-no vac-flu=Transplant recipients who developed influenza in the absence of influenza vaccination Healthy-flu=Healthy people who developed influenza Tx-vac-no flu=Transplant recipients who received influenza vaccination and did not develop influenza N/A=not applicable. ICU=intensive care unit. FEV1=Forced expiratory volume in 1 second. ** 8 patients in the tx-vac-flu group, 4 in the tx-no vac-flu group, none in the healthy-flu group, and 6 in the tx-vac-no flu group had FEV1 measured after a median of 17 months. *P=0.031, †P=0.00007, #P=0.19, compared to the tx-vac-flu group P=not significant for all other comparisons to the tx-vac-flu group in this table.

Table 6: Outcomes.