Animals Dose Vaccine Vaccine+Alum Vaccine+EDO1 Vaccine+EDO2
Balb/c mice 0.5 mla 10/10b 10/10a 10/10a 10/10a
New Zealand rabbits white 2 ml 10/10a 10/10a 10/10a 10/10a
White guinea pigs 2 ml 10/10a 10/10a 10/10a 10/10a
Hamsters 2 ml 10/10a 10/10a 10/10a 10/10a
a5mice, 5 rabbits, 5 hamsters, and 5 guinea pigs, each received the vaccine intra peritoneal (IP) and 5 mice, rabbits, 5 hamsters, and 5 guinea pigs, subcutaneously.
bAll animals survived after vaccination
Table 2: Results of safety trials in animals vaccinated with several adjuvant leptospiral vaccine.