Figure 2: Amino acid alignment of the partial surface antigen including the alpha determinant region. The first line is the consensus sequence corresponding to an HBV subgenotype (B1; accession no. D23678) reference strain retrieved from the DNA DataBank of the Japan/GenBank database. Dots in the alignment indicate positions with amino acids identical to the HBV/B1 consensus sequence. The determinant region is indicated by a different color.