Figure 1: CFU recovered from organs of immunocompetent and immunocompromised mice. (A) Organs CFU estimated 30 (LevRad30) and 90 (LevRad90) days after endovenous or intratracheal inoculation with 3x105 viable radioattenuated yeast cells of P. brasiliensis (LevRad) in immunocompetent mice. Organs CFU were also estimated 30 (C+30) and 90 (C+90) days after infection for the same route with 3x105 viable virulent yeast cells of P. brasiliensis . (B) CFU estimated 30 (LevRad30) days after endovenous or intratracheal inoculation with LevRad in organs from immunocompromised mice. CFU were also estimated 30 days (C+30) after infection with virulent non-irradiated yeast cells of P. brasiliensis . (C) Survival curve of Nude mice. Nude mice were infected intratracheally with 3 x105 yeast cells of virulent P. brasiliensis () or LevRad (◊). The same experiments were repeated twice with similar results.