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Figure 6: (A) Analysis of the putative oligosaccharide binding sites. A-LR7 (residues 795-844) and B-LR are the putative oligosaccharide binding sites of TcdA and TcdB, respectively. Since the crystal structure of A-LR7 was previously published [29], it was used for comparison with the putative oligosaccharide binding sites of TcdB. Identical amino acids are highlighted in red. (B) Amino acid equence analysis of the regions in between the putative oligosaccharide binding sites of TcdB and LR7 of TcdA. Identical amino acids are highlighted in green. |