Advantages |
Limitations |
Easy design and production |
Low immunogenicity |
New molecular biology tools facilitate design and production |
DNA vaccines are poorly immunogenic in humans |
Easy to scale up |
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Large scale production methods available |
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Safe vaccine platform |
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Subunit vaccine; non-infectious, non-replicative; unable to revert to virulent forms |
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Stable formulation |
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Easy storage and shipping; no cold chain requirement for transport |
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Cost effective |
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Immunogenic |
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Can induce both humoral and cellular specific immune responses (including CTL) |
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CTL: Cytotoxic T Cells |
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