| Advantages |
Limitations |
| Easy design and production |
Low immunogenicity |
| New molecular biology tools facilitate design and production |
DNA vaccines are poorly immunogenic in humans |
| Easy to scale up |
|
| Large scale production methods available |
|
| Safe vaccine platform |
|
| Subunit vaccine; non-infectious, non-replicative; unable to revert to virulent forms |
|
| Stable formulation |
|
| Easy storage and shipping; no cold chain requirement for transport |
|
| Cost effective |
|
| Immunogenic |
|
| Can induce both humoral and cellular specific immune responses (including CTL) |
|
| CTL: Cytotoxic T Cells |
|
